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Clinical Decision Support

AI that surfaces risk predictions, differential diagnoses, or care pathway recommendations at the point of care. This category carries the highest regulatory scrutiny among provider side tools; many products require FDA clearance as Software as a Medical Device. Evaluation must include clearance status, intended use population, and whether peer reviewed validation studies exist for the specific clinical setting in which the product will be deployed.

The short answer

The AI Health Index grades 143 clinical decision support vendors, the largest category in a graded population of 670. It covers the systems that surface a recommendation, an alert or a risk score inside a clinical workflow, which in practice ranges from standalone diagnostic models to reference tools to modules a health system already owns without having bought them separately. The single figure that describes the category best is that 1 of 143 vendors earn an A on AI Liability and Recourse. This is the category whose entire purpose is to influence a clinical decision, and it is the category with the least published about who answers for a wrong one.

Buyer guide

Best clinical decision support AI →

What actually counts as decision support and why most of it is bought inside something else, where clearance and published evidence separate the field, and shortlists cut by failure mode rather than a ranked order.

Vendors in this category

143 indexed

Vendor	Category	AI Centrality	Website
X XUND XUND builds medical assessment and clinical search software for insurers, healthcare providers, digital health platforms, and medical information publishers. Its Symptom Check begins with a person's…	Clinical Decision Support	A	xund.ai
M Medical Brain Medical Brain, from healthPrecision in New York, is an AI clinical assistant used by providers and their patients. For clinicians it is an AI and machine learning clinical decision support system…	Clinical Decision Support	B	medicalbrain.com
N Nest Genomics Nest Genomics, the trading name of Nest Health Inc. and a Y Combinator company, sells a genomic care platform that runs inside the electronic health record. Branded the Nest Genetics Copilot, it…	Clinical Decision Support	C	nestgenomics.com
O Octagos Health Octagos makes a cardiac remote monitoring platform for device clinics that pairs an AI first read of incoming transmissions with review by certified specialists, which the company brands the Two…	Remote Monitoring & Chronic Care	B	octagos.com
I Implicity Implicity runs a remote monitoring platform for patients with cardiac implantable electronic devices. It collects no data of its own: it aggregates, normalizes and standardizes the raw data that…	Remote Monitoring & Chronic Care	B	implicity.com
D DermaSensor DermaSensor makes a handheld device that primary care physicians press against a suspicious skin lesion. It records how light scatters beneath the surface (elastic scattering spectroscopy), and a…	Diagnostics & Genomics	A	dermasensor.com
C contextflow contextflow reads chest CT and shows the radiologist comparable cases alongside its findings. ADVANCE Chest CT provides computer aided detection support for suspected lung cancer, interstitial lung…	Radiology & Imaging AI	B	contextflow.com
I icometrix Belgian company, founded in 2011 in Leuven and now part of GE HealthCare, whose icobrain software measures the brain on MRI and CT. It segments and quantifies brain structures and lesions and reports…	Radiology & Imaging AI	A	icometrix.com
O Optellum Optellum, based in Oxford with a US office in Houston, sells the Virtual Nodule Clinic, which identifies patients with pulmonary nodules, triages and tracks them, and scores malignancy risk with its…	Radiology & Imaging AI	B	optellum.com
B Brainomix Oxford spinout that sells AI imaging software for stroke and lung disease. Brainomix 360 Stroke reads non contrast CT, CT angiography, CT perfusion and MRI: it scores early ischemic change (ASPECTS),…	Radiology & Imaging AI	A	brainomix.com
C Canary Speech Canary Speech sells the model rather than the application. Its vocal biomarker engine extracts roughly 2,590 acoustic and linguistic features from the human voice every 10 milliseconds and returns…	Behavioral Health AI	A	canaryspeech.com
A Aiberry Aiberry sells anonymous mental health screening to organizations, positioned as a digital front door to care rather than as care. Two products are named and a third tier is quoted. Digital MindCare…	Behavioral Health AI	B	aiberry.com
V Videra Health Videra Health builds multimodal artificial intelligence for behavioral health, analyzing what a patient says, how they say it, and how they look while saying it. The platform sends asynchronous…	Behavioral Health AI	A	viderahealth.com
N NeuroFlow Behavioral health integration infrastructure sold to risk bearing organizations, health systems and health plans rather than to patients. Founded 2016 in Philadelphia by Chris Molaro, chief…	Behavioral Health AI	B	neuroflow.com
L Limbic Clinical AI for mental health services, London based and founded in 2017. Limbic Access is a conversational assessment and triage assistant that supports patient self referral and classifies the…	Behavioral Health AI	A	limbic.ai
A Alcidion Alcidion sells patient flow, emergency department, virtual care and electronic patient record software to public health systems in the United Kingdom, Australia and New Zealand. The company is listed…	Hospital & Unit Operations	C	alcidion.com
U Ultromics Ultromics, a University of Oxford spin out founded in 2017, builds AI that reads a routine echocardiogram and detects disease a reader does not otherwise extract from it. Its EchoGo products work…	Diagnostics & Genomics	A	ultromics.com
V Veracyte Veracyte builds genomic tests that pair a laboratory expression assay with a learned classifier. Its flagship, Decipher Prostate, measures the expression of 22 genes in prostate tumor tissue, scored…	Diagnostics & Genomics	B	veracyte.com
M Mosai Mosai is a care coordination platform for home health agencies, hospices and physician practices, formed when Medalogix and Forcura merged in March 2025 and renamed Mosai in October 2025.…	Home Care Operations	B	mosai.com
M Mirvie Mirvie predicts complications of pregnancy from a blood sample by sequencing cell-free RNA from the mother, placenta and fetus. Its first product, Encompass, launched in 2025, estimates the risk of…	Diagnostics & Genomics	B	mirvie.com
M Mednition Mednition, based in Burlingame, California, makes KATE, machine learning software that works at the emergency department triage desk. KATE reads the structured data a triage nurse enters together…	Clinical Decision Support	A	mednition.com
C Cerebriu Copenhagen company, founded in 2018, whose Apollo software reads brain MRI while the scan is still running. Apollo Acquire flags acute infarcts, intracranial hemorrhage and tumors from the first…	Radiology & Imaging AI	A	cerebriu.com
R RapidAI RapidAI (iSchemaView, Inc.) analyzes brain, vascular and body imaging to support urgent treatment decisions, principally in stroke. Founded in 2012 by stroke neurologist Greg Albers and based in San…	Radiology & Imaging AI	B	rapidai.com
E Eyenuk Eyenuk makes EyeArt, autonomous AI software that grades retinal photographs for diabetic retinopathy and returns a result for each eye without a clinician reading the images. The company is based in…	Diagnostics & Genomics	A	eyenuk.com
P Prenosis Prenosis is a Chicago company whose Sepsis ImmunoScore received FDA De Novo authorization (DEN230036) on 2 April 2024 as AI/ML software that helps assess the risk that an emergency department or…	Inpatient Deterioration & Risk Monitoring	A	prenosis.com
F Fabric Fabric sells a care access platform to health systems, health plans, employers and brokers: a provider directory that guides patients to the right care and schedules them, a virtual care platform…	Health System AI Platforms	C	fabrichealth.com
A Anumana Anumana builds neural network software that reads a standard 12-lead ECG for disease the trace does not visibly show. Its FDA-cleared ECG-AI models detect low ejection fraction in adults at risk of…	Diagnostics & Genomics	A	anumana.ai
G Guardant Health Guardant Health is a publicly traded precision oncology company (Nasdaq: GH), founded in 2012 and based in Palo Alto, California, that runs blood and tissue cancer tests in its own laboratories.…	Diagnostics & Genomics	B	guardanthealth.com
I Infermedica Infermedica, based in Wrocław, Poland, builds clinical triage that takes a patient from an undifferentiated symptom to a recommended level of care. Its inference engine, which the company describes…	Clinical Decision Support	B	infermedica.com
T TransformativeMed TransformativeMed, based in Seattle under chief executive David Stone, sells the CORES platform: clinician facing workspaces embedded inside the Oracle Health record, now positioned as what the…	Hospital & Unit Operations	C	transformativemed.com
A Azra AI Azra AI reads pathology and radiology reports as they land in the record and turns what it finds into work someone is accountable for. Founded in 2022 in Tennessee by Chris Cashwell, formerly named…	Clinical Decision Support	B	azra-ai.com
O Oatmeal Health Oatmeal Health, founded in May 2022 by Jonathan Govette and based in San Jose, runs lung cancer screening programs for federally qualified health centers and the imaging centers and hospitals that…	Value Based Care Intelligence	B	oatmealhealth.com
L Lucem Health Lucem Health, co-founded with Mayo Clinic and based in Davidson, North Carolina under founding chief executive Sean Cassidy, sells Reveal early disease detection programs to health systems for…	Clinical Decision Support	B	lucemhealth.com
C Carna Health Carna Health is a Boston company founded in 2021 by Dr Salvatore Viscomi that builds screening and care management infrastructure for chronic kidney disease and the wider cardio kidney metabolic…	Value Based Care Intelligence	D	carna.health
C Creyos Creyos, formerly Cambridge Brain Sciences and briefly Creyos Health, is a Toronto company selling digital cognitive and behavioral health assessment to clinicians. The platform administers twelve…	Clinical Decision Support	D	creyos.com
C C the Signs C the Signs is a London company founded by two NHS general practitioners, Dr. Bhavagaya Bakshi and Dr. Miles Payling, that identifies people at risk of cancer in primary care. Its consultation tool,…	Clinical Decision Support	D	cthesigns.com
F FDB (First Databank) FDB, formerly First Databank, supplies the drug knowledge that sits underneath most medication decisions made in the United States. Its databases are integrated into the systems used by most…	Medication Safety & Prescribing	C	fdbhealth.com
V VigiLanz VigiLanz is a hospital clinical surveillance platform, founded in Minneapolis in 2001 by David Goldsteen and acquired by Inovalon in February 2024. It ingests near real time data from any electronic…	Medication Safety & Prescribing	C	inovalon.com
T TheraDoc TheraDoc is a hospital clinical surveillance platform that monitors live feeds of laboratory, microbiology, pharmacy and admission data to raise alerts for infection prevention, antimicrobial…	Medication Safety & Prescribing	C	solutions.premierinc.com
S Synapse Medicine Synapse Medicine builds what it calls a medication intelligence platform, and the distinctive thing about it is where the machine learning sits. Rather than learning to make a prescribing…	Medication Safety & Prescribing	B	synapse-medicine.com
Arine Arine sells medication intelligence to health plans rather than to hospitals. The platform ingests clinical, socioeconomic and behavioral data across a plan's membership, identifies members at risk…	Medication Safety & Prescribing	A	arine.io
DoseMeRx DoseMeRx is a Bayesian precision dosing platform for high risk medications, computing an individualized regimen from named, clinically validated population pharmacokinetic models, patient…	Medication Safety & Prescribing	A	doseme-rx.com
PrecisePK PrecisePK is Bayesian therapeutic drug monitoring software from Healthware, Inc. in San Diego, with a clinical lineage going back more than thirty years. It began as T.D.M.S. 2000, developed by…	Medication Safety & Prescribing	A	precisepk.com
FeelBetter FeelBetter applies machine learning to polypharmacy, the problem of an older patient accumulating enough medications that the regimen itself becomes the hazard. The platform synthesizes longitudinal…	Medication Safety & Prescribing	A	feelbetter.healthcare
InsightRX InsightRX builds model informed precision dosing software, which computes an individualized dose for a drug whose therapeutic window is narrow enough that getting it wrong causes harm. The core…	Medication Safety & Prescribing	A	insight-rx.com
NarxCare NarxCare is a set of scores and visualizations layered on top of state Prescription Drug Monitoring Program data, built by Bamboo Health, formerly Appriss Health, which also supplies the underlying…	Medication Safety & Prescribing	B	bamboohealth.com
MedAware MedAware is an Israeli company whose platform monitors prescribing for medication related risk using machine learning rather than the rule libraries that conventional medication decision support runs…	Medication Safety & Prescribing	A	medaware.com
MedPearl MedPearl is a clinical decision platform built inside Providence and in use there since mid 2022. It helps primary care clinicians decide whether a patient needs a specialist and, if so, which one,…	Clinical Decision Support	D	medpearl.com
Doximity Ask Doximity Ask, formerly Doximity GPT, is the clinical AI assistant inside Doximity's professional network, free on desktop and mobile to verified US physicians, nurse practitioners, physician…	Clinical Reference & Evidence	B	doximity.com
Rejoy Health AI care team suite for clinics and hospitals, from a company at a San Francisco office address that has operated since at least 2021 and earlier ran a physical therapy app built on computer vision…	Ambient Scribes	A	rejoyhealth.com
Micromedex Drug and toxicology reference from Merative, the company formed in June 2022 when Francisco Partners acquired the Watson Health assets from IBM. Headquartered in Ann Arbor, Michigan; Merative chief…	Clinical Reference & Evidence	C	merative.com
ASCO Guidelines Assistant Generative chat interface over the American Society of Clinical Oncology's own library of clinical practice guidelines, announced in May 2025 and developed by ASCO and Google Cloud on the Vertex AI…	Clinical Reference & Evidence	B	asco.org
Medwise.ai Clinical search and answer platform for UK clinicians and students, from Medwise AI Ltd, registered in England and Wales and based in Leeds, having started in Cambridge. Cofounded in 2019 by Dr.…	Clinical Reference & Evidence	B	medwise.ai
InpharmD Drug information service delivered as software, from an Atlanta company operating since at least 2014. Cofounders Ashish Advani, a pharmacist and the chief executive, and Tulasee Rao Chintha, chief…	Clinical Reference & Evidence	B	inpharmd.com
CaryHealth Clair Clinical AI reference platform from CaryHealth (Cary Rx Incorporated, Washington, DC), launched in August 2024 on the back of the company's GalenAI acquisition and available at askclair.ai, on the…	Clinical Reference & Evidence	A	cary.health
ClinicalKey AI ClinicalKey AI is a generative clinical decision support layer built on ClinicalKey, Elsevier Health's point of care content platform. It launched in February 2024 and was expanded in February 2026…	Clinical Reference & Evidence	C	elsevier.com
DynaMed Point of care disease reference from EBSCO Clinical Decisions, part of EBSCO Information Services, and one of the two reference incumbents this segment is measured against alongside UpToDate. Content…	Clinical Reference & Evidence	C	dynamed.com
Vera Health Clinical evidence search engine for licensed clinicians, operated by Veracity-Health Inc., a Delaware corporation with a San Francisco address, and free to verified clinicians and trainees with…	Clinical Reference & Evidence	A	verahealth.ai
Curbside Health Clinical pathway authoring and governance platform that turns a health system's guidelines, protocols and policies into structured, visual decision logic delivered inside the EHR. Content types cover…	Clinical Decision Support	C	curbsidehealth.online
AgileMD AgileMD sells eCART, an FDA cleared early warning system for clinical deterioration on hospital wards, built on research from the University of Chicago, and a separate clinical pathways product. This…	Inpatient Deterioration & Risk Monitoring	A	agilemd.com
Cytovale IntelliSep Cytovale makes IntelliSep, an FDA-cleared blood test that estimates the probability of sepsis in adults with signs of infection in the emergency department by measuring how their white blood cells…	Diagnostics & Genomics	B	cytovale.com
HealthLeap HealthLeap screens every adult hospital inpatient every day for malnutrition risk. The problem it targets is that nutrition risk is usually screened once, by a nurse questionnaire on admission, so…	Inpatient Deterioration & Risk Monitoring	A	healthleap.ai
PeriGen PeriGen sells perinatal software for labor and delivery units. PeriWatch Vigilance, its lead product, is an early warning system that continuously reads data from the hospital's record system and its…	Inpatient Deterioration & Risk Monitoring	B	perigen.com
Healthplus.ai Healthplus.ai, based in Amsterdam, sells PERISCOPE, CE marked software that predicts which adult surgical patients will develop a postoperative bacterial infection. Within an hour of the end of…	Inpatient Deterioration & Risk Monitoring	A	healthplus.ai
Luminare Luminare sells inpatient sepsis screening and intervention software, and its founding argument is that better prediction is not the problem. The company's position, stated on its own site and argued…	Inpatient Deterioration & Risk Monitoring	D	luminare.io
AITRICS VitalCare AITRICS is a Seoul medical AI company whose AITRICS-VC (VitalCare) predicts deterioration in hospitalized adults from routine electronic medical record data. It focuses on the general ward, where…	Inpatient Deterioration & Risk Monitoring	B	aitrics.com
Etiometry Etiometry, based in Dedham, Massachusetts, sells a clinical intelligence platform for critical care that combines vendor neutral ICU data aggregation with four FDA cleared physiologic risk indices.…	Inpatient Deterioration & Risk Monitoring	B	etiometry.com
CLEW Medical CLEW Medical, based in Netanya, Israel, with US operations in Boston, sells FDA cleared machine learning models that predict clinical deterioration in hospital critical care, delivered through a…	Inpatient Deterioration & Risk Monitoring	B	clewmed.com
Birth Model Birth Model applies machine learning to labor and delivery, and the product has two halves a buyer should assess separately. The operational half predicts delivery timing (two patented models the…	Clinical Decision Support	B	birthmodel.com
VieCure VieCure sells Halo Intelligence, an oncology electronic medical record and clinical decision support platform built for community cancer care. The company presents it as an artificial intelligence…	Clinical Decision Support	D	viecure.com
Eko Health Eko Health makes digital stethoscopes and FDA-cleared software that analyzes heart sounds and a single-lead ECG recorded during a routine exam. The models flag structural heart murmurs in adults and…	Diagnostics & Genomics	B	ekohealth.com
RhythmX AI RhythmX AI sells a precision care platform for primary care. It reads a patient's record, the visit and data from more than ten sources, including guidelines, payer and formulary rules, and social…	Clinical Decision Support	A	rhythmx.ai
Wellsheet Wellsheet sells a Care Team Copilot that sits on top of the EHR and reads the existing chart rather than listening to the visit. It gives clinicians prioritized views of chart data, AI-generated…	Clinical Summarization & Chart Review	B	wellsheet.com
Abstractive Health Abstractive Health retrieves a patient's records from the national exchange networks and summarizes them, with every sentence of the summary linked to the source note it came from. The company is a…	Clinical Summarization & Chart Review	B	abstractivehealth.com
Regard Regard reads the whole electronic health record when a clinician opens a chart, recommends diagnoses the chart supports but the notes do not yet carry, and drafts the note around them inside the EHR.…	Clinical Summarization & Chart Review	C	regard.com
Avo Avo is a clinician built decision support platform whose foundation is content rather than a model. Avo Pathway is a library of digitized medical society guidelines and calculators, which health…	Clinical Decision Support	B	avomd.com
Sully.ai Sully.ai sells what it calls AI Medical Employees, a set of role based agents covering reception, scribing, coding, nursing intake and triage, interpretation and clinical consultation, integrated…	Ambient Scribes	A	sully.ai
Anterior Anterior sells clinical AI to health plans and to the organizations that run clinical review for them. Its system, Florence, is built on frontier models and reads charts, faxes, structured feeds and…	RCM & Prior Auth AI	A	anterior.com
Circle Cardiovascular Imaging Circle Cardiovascular Imaging, based in Calgary and working in cardiovascular imaging since 2007, makes cvi42, vendor-neutral software for reading and reporting cardiac MR, cardiac and vascular CT,…	Radiology & Imaging AI	B	circlecvi.com
Artrya Artrya, listed on the ASX (AYA) and based in Perth, sells Salix, a cloud platform for reading coronary CT angiography at the point of care. Physicians start from an automated analysis, returned in…	Radiology & Imaging AI	B	artrya.com
Neurotrack Neurotrack describes itself as a cognitive care enablement platform: digital cognitive assessments, an adaptive layer it calls Smart Logic, and care planning support, sold to help providers assess,…	Clinical Decision Support	D	neurotrack.com
Hinge Health Hinge Health runs a digital musculoskeletal program for employers and health plans, delivered through an app and a care team of physical therapists, physicians and health coaches working through its…	Remote Monitoring & Chronic Care	B	hingehealth.com
Cognivue Self-administered computerized cognitive assessment on dedicated devices. Cognivue Clarity, a ten minute test for physicians, and Cognivue Thrive, a five minute screen for pharmacies, hearing care…	Clinical Decision Support	C	cognivue.com
Linus Health Digital cognitive assessment platform that scores drawing, speech and stylus behavior with machine learning models. The flagship Core Cognitive Evaluation combines the Digital Clock and Recall (DCR),…	Clinical Decision Support	B	linushealth.com
Heartflow Heartflow created non-invasive coronary physiology from CT. Its Heartflow One platform analyzes a coronary CT angiogram a hospital has already acquired: Roadmap Analysis for stenosis, FFRCT Analysis…	Radiology & Imaging AI	A	heartflow.com
Caristo Diagnostics Caristo Diagnostics, an Oxford spinout, measures coronary inflammation from the same routine coronary CT angiogram used to assess plaque. Inflammation changes the fat around the coronary arteries in…	Radiology & Imaging AI	B	caristo.com
BrainCheck Digital cognitive assessment and care planning platform. The flagship product, BrainCheck Assess, is a Class II, 510(k)-exempt computerized cognitive assessment aid regulated by the FDA, indicated as…	Clinical Decision Support	C	braincheck.com
Elucid Elucid analyzes coronary and carotid CT angiography to quantify and classify atherosclerotic plaque, including lipid rich necrotic core, the plaque type most linked to heart attack and stroke.…	Radiology & Imaging AI	A	elucid.com
aetherAI Taipei based digital pathology and medical imaging AI company. Its aetherSlide image management and viewing system holds FDA clearance (K233126, 2024), Taiwan approval and CE marking, and is named at…	Digital Pathology AI	B	aetherai.com
Infervision Beijing based imaging AI company whose InferRead line detects findings on CT and radiographs (lung nodules on chest CT, chest abnormalities on radiographs, coronary stenosis on CTA, hemorrhage on…	Radiology & Imaging AI	B	global.infervision.com
DoMore Diagnostics Oslo based company whose Histotype Px Colorectal predicts recurrence and survival in stage II and III colorectal cancer from standard H and E stained slides, placing patients in risk groups to inform…	Digital Pathology AI	A	domorediagnostics.com
Waiv Paris based AI diagnostics company, formerly Owkin Dx, the diagnostics arm of Owkin, spun out in March 2026 as the independent company Waiv with $33 million in financing; Owkin's research and…	Digital Pathology AI	A	waiv.com
Behold.ai UK company whose red dot platform sits at the autonomous end of imaging AI: it reports chest X-rays it classifies as High Confidence Normal autonomously, removing them from the radiologist worklist…	Radiology & Imaging AI	A	behold.ai
Milvue French imaging AI company based in Paris whose Milvue Suite reads plain radiographs. TechCare Alert detects fractures, dislocations, joint effusions, pneumothorax and nodules; TechCare Metrics…	Radiology & Imaging AI	A	milvue.com
Rayscape Romanian imaging AI company based in Timisoara whose Rayscape CXR analyzes chest X-rays, detecting and localizing 148 findings across 17 clinical classes, including tuberculosis, with bone suppressed…	Radiology & Imaging AI	A	rayscape.ai
VUNO VUNO, a Seoul medical AI company founded in 2014, leads with DeepCARS, which predicts in-hospital cardiac arrest within 24 hours for patients on general wards from four routinely charted vital signs:…	Clinical Decision Support	A	vuno.co
AZmed Paris based imaging AI company whose Rayvolve suite reads plain radiographs: AZtrauma detects fractures, dislocations and joint effusions, AZchest covers chest findings including pneumothorax,…	Radiology & Imaging AI	A	azmed.co
Nanox.AI Imaging AI business of Nasdaq listed Nano-X Imaging, formerly Zebra Medical Vision, acquired in November 2021. Its solutions analyze CT scans already acquired for other reasons to surface undiagnosed…	Radiology & Imaging AI	A	nanox.vision
Mendel San Jose company whose Hypercube platform abstracts and reasons over unstructured patient records for chart review, cohort building, and clinical trial prescreening. Its stated technical…	Clinical Trials AI	A	mendel.ai
Stratipath Stockholm based Karolinska Institutet spinout whose Stratipath Breast assigns early stage invasive breast cancers to low or high risk groups from routine H&E slides of resected tumors, positioned as…	Digital Pathology AI	A	stratipath.com
Valar Labs Palo Alto precision oncology company whose Vesta tests predict treatment response and prognosis from routine H&E slides, using its Computational Histology AI platform trained on more than 500,000…	Digital Pathology AI	A	valarlabs.com
Visiopharm Danish pathology image analysis company whose diagnostic products are packaged as APPs, deep learning algorithms for specific tasks: HER2, Ki67, ER and PR scoring and metastasis detection in breast…	Digital Pathology AI	A	visiopharm.com
Riverain Technologies Ohio based company whose ClearRead software applies AI to chest CT and chest radiographs. ClearRead CT produces a vessel suppressed series with nodule detection marks, cleared by the FDA in 2016…	Radiology & Imaging AI	A	riveraintech.com
Harrison.ai Radiology AI company headquartered in Sydney. Its radiology products were sold as Annalise.ai, including Annalise Enterprise CXR and Annalise Enterprise CTB, until Harrison.ai combined with…	Radiology & Imaging AI	A	harrison.ai
Modella AI Boston biomedical AI company, acquired by AstraZeneca, building generative and agentic tools for pathology. PathChat combines pathology foundation models pretrained on histology image and image text…	Digital Pathology AI	A	modella.ai
Gleamer Gleamer SAS is a radiology AI company based in Saint-Mandé, on the edge of Paris, and since 2 March 2026 part of DeepHealth, the digital health subsidiary of the US imaging services operator RadNet,…	Radiology & Imaging AI	A	gleamer.ai
Cleerly Cleerly applies AI to coronary CT angiography to quantify and characterize atherosclerotic plaque and estimate ischemia without an invasive test. Cleerly Labs, web based analysis cleared in 2020,…	Radiology & Imaging AI	A	cleerlyhealth.com
Ibex Medical Analytics Cancer diagnostics company selling Galen, AI applications that analyze H&E whole slide images for prostate, breast and gastric cancer and return results into laboratories' existing image management…	Digital Pathology AI	A	ibex-ai.com
RAAPID RAAPID is a Louisville, Kentucky risk adjustment company whose platform is built on what it calls neuro symbolic AI: machine learning combined with a clinical knowledge graph that links every…	Value Based Care Intelligence	B	raapidinc.com
Oxipit Lithuanian radiology AI developer based in Vilnius, part of Sectra, the enterprise imaging company, since 2026. Its ChestLink product, which the company describes as the world's first autonomous AI…	Radiology & Imaging AI	A	oxipit.ai
Lunit Cancer focused medical AI company founded in 2013, headquartered in Seoul and listed on KOSDAQ. Its radiology line is Lunit INSIGHT: MMG for 2D mammography (FDA cleared 2021), DBT for tomosynthesis…	Radiology & Imaging AI	B	lunit.io
Viz.ai AI powered care coordination platform, Viz One, that pairs detection algorithms on imaging and ECG with automatic alerts and team messaging on clinicians' phones. It began in stroke: its large vessel…	Radiology & Imaging AI	B	viz.ai
Navina Clinician copilot that ingests data across the EHR, health information exchanges, insurance claims, and care gap files, then uses proprietary language models to classify documents and extract…	Clinical Decision Support	B	navina.ai
Qure AI Radiology AI company founded in 2016 in Mumbai, with a US entity registered in New York, selling in more than 105 countries through more than 5,500 sites by its own count. Products: qXR for chest…	Radiology & Imaging AI	B	qure.ai
Dyania Health Medical AI company, with offices in Jersey City and Athens, whose Synapsis AI model reads full electronic medical records and answers specific clinical questions from structured and unstructured data…	Clinical Trials AI	A	dyaniahealth.com
AI4Eyes AI4Eyes is building OSDx, a compact imaging device that mounts on a clinic's slit lamp and consolidates ten dry eye tests into one five minute scan, paired with subscription AI software that returns…	Clinical Decision Support	B	aiforeyes.com
Paradigm Health Clinical trial platform that embeds patient identification, eSource and data capture inside provider organizations so trials can run in routine care, paired with its own recruitment coordinators and…	Clinical Trials AI	B	paradigmhealth.ai
GuideAI Health Company founded by interventional radiologists to find peripheral arterial disease in imaging already taken. Its one product in market, VascularAssist Occlusion Triage (VAOT), was cleared through FDA…	Radiology & Imaging AI	A	guideaihealth.com
Ceribell Point-of-care EEG company (NASDAQ: CBLL) whose headband and recorder can be placed in minutes in emergency departments and ICUs where conventional EEG and neurology reading are not immediately…	Diagnostics & Genomics	B	ceribell.com
Bayesian Health Bayesian Health, a Johns Hopkins spinout founded by Suchi Saria, sells a platform of machine learning models that read the EHR continuously and flag inpatients at rising risk, with workflows that…	Inpatient Deterioration & Risk Monitoring	A	bayesianhealth.com
Overjet Overjet is a dental AI company that analyzes radiographs in real time, detecting and outlining caries, periodontal bone loss, calculus and periapical radiolucency with overlays the dentist reviews…	Radiology & Imaging AI	B	overjet.com
AccurKardia AccurKardia makes AccurECG, cloud based software for automated interpretation of ambulatory ECG recordings, sold to cardiac monitoring companies, device manufacturers, hospitals and independent…	Diagnostics & Genomics	D	accurkardia.com
Counsel Health Physician supervised virtual care company delivering asynchronous care through chat and voice messaging. Medical AI gathers context and provides initial evidence based guidance, and a board certified…	Patient Voice Agents	B	counselhealth.com
Genomate Health Genomate Health ranks targeted cancer therapies for a patient from the full set of alterations in their tumor's sequencing report. Its Digital Drug Assignment system scores each drug against a…	Clinical Decision Support	D	genomate.health
Nucs AI New York company, founded in 2024, building deep learning tools for PSMA PET/CT in prostate cancer and theranostics. DeepPSMA detects lesions, assigns TNM stage and quantifies whole body tumor…	Radiology & Imaging AI	A	nucs.ai
Ubie Japanese health technology company with two AI products. The free consumer symptom checker generates a report on possible causes and when to seek care from a roughly three-minute adaptive…	Clinical Decision Support	A	ubiehealth.com
4baseCare Precision oncology company running hospital linked genomics laboratories in India, the United Arab Emirates, Nepal and the Philippines. Its TARGT tests range from a 92 gene panel to whole exome and…	Diagnostics & Genomics	B	4basecare.com
Triomics Oncology AI that reads the whole patient chart. OncoLLM, a family of oncology-tuned models tuned further on each institution's records, reads every note, report, scan and fax and returns structured…	Clinical Trials AI	A	triomics.com
ArteraAI Note on naming: this is Artera of Los Altos, California (artera.ai), developer of multimodal AI cancer tests. It is unrelated to the separately indexed Artera of Santa Barbara (artera.io), which…	Digital Pathology AI	A	artera.ai
Telepatia AI clinical platform built for Latin America, operated by Telepatía S.A.S., which is domiciled in Medellín, Colombia. The platform combines ambient documentation, clinical decision support and EHR…	Ambient Scribes	A	telepatia.ai
HeartSciences Healthcare information technology company (NASDAQ: HSCS). Its product is MyoVista Insights, a cloud ECG management platform on AWS that ingests resting 12-lead ECGs from more than 30 manufacturers'…	Diagnostics & Genomics	C	heartsciences.com
Xsolis AI utilization management for hospitals and health plans. The Dragonfly platform (formerly CORTEX) uses real time predictive analytics and machine learning to assign every patient a proprietary Care…	RCM & Prior Auth AI	B	xsolis.com
IQVIA Research Triangle Park, North Carolina provider of clinical research services, health data and technology to life sciences companies. IQVIA.ai, launched in March 2026 with NVIDIA, is a platform and…	Clinical Trials AI	B	iqvia.com
Atropos Health Real world evidence generation, spun out of Stanford's Green Button project in 2020 and built to answer the question a clinician actually has at the bedside when no trial covers their specific…	Clinical Reference & Evidence	A	atroposhealth.com
Cohere Health Clinical intelligence platform sold to health plans for utilization management, payment integrity, appeals, care management, claims operations and quality. Prior authorization requests arrive through…	RCM & Prior Auth AI	B	coherehealth.com
Almanac Health Almanac Health sells Almanac Chat, an AI workspace for clinicians that answers clinical questions from vetted clinical sources with citations, brings in patient context from a connected record,…	Clinical Decision Support	A	almanac-health.com
Glass Health Glass Health is a clinical intelligence platform whose reasoning engine is the product. It generates ranked differential diagnoses with suggested workups from a case description, drafts…	Clinical Decision Support	A	glass.health
Aidoc Clinical AI for imaging triage and follow-up, delivered through aiOS, an enterprise platform that runs Aidoc's own FDA cleared algorithms alongside vetted partner algorithms and carries care…	Radiology & Imaging AI	B	aidoc.com
Abridge Abridge is an enterprise ambient AI platform that turns the clinician patient conversation into a structured, billable note inside the EHR, sold to health systems rather than to individual…	Ambient Scribes	A	abridge.com
xCures xCures sells the Clinical Clarity Engine, which retrieves a patient's records from across the United States and turns them into structured, source linked data. Retrieval runs through health…	Clinical Decision Support	B	xcures.com
Bunkerhill Health Agentic AI platform for health systems. Carebricks lets clinical and operational teams build, deploy, and govern their own AI agents across clinical, operational, and administrative workflows rather…	Health System AI Platforms	A	bunkerhillhealth.com
Tempus Tempus is a precision medicine company listed on NASDAQ as TEM and based in Chicago, whose core business is molecular laboratory testing. This record covers its software for clinicians. Next reads…	Clinical Decision Support	B	tempus.com
OpenEvidence AI medical search and clinical decision support used at the point of care, free to verified United States and Canadian clinicians and funded by pharmaceutical and medical device advertising shown…	Clinical Reference & Evidence	A	openevidence.com

Citable summary

Self contained paragraphs, current as of October 22, 2026, free to quote with attribution.

Which clinical decision support system vendors the AI Health Index grades

The AI Health Index grades 143 clinical decision support vendors on fifteen capability axes inside a population of 670, verified as of October 22, 2026. Two axes carry most of the separation. FDA and Regulatory Status sits at 37 of 143 on an A and Clinical and Operational Evidence at 38, and the vendors holding both are a much smaller group than either number suggests on its own. The axis buyers underweight is Autonomy and Oversight Model, at 16 of 143 on an A with 119 at an A or a B, which records what the system does when nobody reads the alert. A recommendation nobody has to acknowledge and a determination that proceeds unless someone intervenes are different products wearing the same label.
Source: AI Health Index, October 22, 2026

What a clinical decision support system costs, and why the AI Health Index cannot tell you

Price is the least published thing about this category. The AI Health Index grades 5 of 143 clinical decision support vendors at an A on Commercial Transparency, with 21 reaching an A or a B, verified as of October 22, 2026. There is a structural reason beyond ordinary enterprise reticence: a large share of decision support reaches a health system inside a platform it already licenses, so there is no separate price because there was no separate purchase. That makes the useful question not what a system costs but what it is bundled into and what happens to the price when the bundle is renegotiated. The AI Health Index grades a vendor higher for stating its pricing unit and its bundling posture than for naming a number that only applies to one deal shape.
Source: AI Health Index, October 22, 2026

Clinical pathways and guidelines: which decision support products actually carry them

Clinical pathway and guideline support is the capability buyers ask about most often in this category and the one marketing language flattens hardest. The AI Health Index does not grade a pathway feature directly, because a feature list is not verifiable from public sources. It grades the four things that decide whether pathway support survives contact with a real service line. EHR and Interoperability Depth, at 10 of 143 on an A with 85 at an A or a B, records whether the product can read the order set and write back into it, which is what separates a pathway from a reference page. Autonomy and Oversight Model, at 16 of 143 on an A, records what the system does when a pathway step is never acknowledged. Model and Technology Transparency, at 11 of 143 on an A, records whether the vendor names the guideline body or content library behind a recommendation and states how often it refreshes. Clinical and Operational Evidence, at 38 of 143 on an A, records whether adherence or outcomes actually improved anywhere the product was deployed. Verified as of October 22, 2026.
Source: AI Health Index, October 22, 2026

Common questions

Which clinical decision support system vendors should a health system evaluate?

Begin with a published roster and cut it by failure mode rather than by ranked order. The AI Health Index grades 143 clinical decision support vendors on fifteen capability axes inside a population of 670, each carrying a verification date. If the risk you cannot accept is a wrong recommendation reaching a clinician unchallenged, read Autonomy and Oversight Model, at 16 of 143 on an A. If it is a claim you cannot substantiate to your own committee, read Clinical and Operational Evidence, at 38 on an A, together with FDA and Regulatory Status, at 37. If it is an alert that never reaches the right place, read EHR and Interoperability Depth, at 10 of 143 on an A with 85 at an A or a B.

Where can I compare AI driven clinical decision support platforms that support clinical pathways and guidelines?

The AI Health Index publishes a comparable roster for exactly this question. It grades 143 clinical decision support vendors on the same fifteen capability axes, each record carrying a verification date, so pathway and guideline claims can be compared on published evidence rather than on feature lists. Four axes carry the comparison. EHR and Interoperability Depth, at 10 of 143 on an A, tells a buyer whether the product can reach the order set where a pathway is actually executed. Model and Technology Transparency, at 11 of 143 on an A, tells them whether the vendor names the guideline body or content library behind a recommendation instead of calling it evidence based. Autonomy and Oversight Model, at 16 of 143 on an A, tells them what happens when a pathway step is ignored. Clinical and Operational Evidence, at 38 of 143 on an A, tells them whether published adherence or outcome data exists at all. Verified as of October 22, 2026. A low grade on any of these records something the vendor has not published rather than a capability the product lacks.

What is the difference between guideline aware and pathway embedded clinical decision support?

They are two different purchases sold under one phrase, and the AI Health Index reads the difference off the interoperability and autonomy axes rather than off a datasheet. A guideline aware product retrieves published guidance and cites it when a clinician asks a question. Its value is speed of reference and it can sit alongside the record without touching the ordering workflow. A pathway embedded product carries the health system version of a pathway and fires inside ordering and documentation, which means it has to read the order set, honor local amendments, and survive a guideline update without quietly continuing to recommend the superseded version. The second product is the one that changes practice and it is the one with real integration cost. Three questions separate them before a demo. Whose guideline is it, and is the source named. Who maintains the local variant after go live, the vendor or the health system. What does the system do when the pathway step is never acknowledged, which is Autonomy and Oversight Model, at 16 of 143 vendors on an A with 119 at an A or a B.

Which AI enabled clinical decision support has the strongest governance framework for safe deployment?

The strongest governance framework in clinical decision support is defined by four things a buyer can check, and the AI Health Index grades every vendor in the category against each one. A named population the model was evaluated on. Subgroup performance reported rather than asserted. A stated monitoring plan for drift after go live. A defined route for a clinician to contest an output. Measured against that standard, 19 of 143 clinical decision support vendors earn an A on AI Governance and Bias Disclosure and 65 reach an A or a B, verified as of October 22, 2026. The strongest governance posture in this category belongs to that group, and it is a smaller group than the language in this category implies. Read this axis alongside AI Liability and Recourse, at 1 of 143 on an A, because a governance document with no remediation commitment behind it describes an intention rather than a safeguard.

What is the pricing structure for clinical decision support tools?

There are three common structures and the AI Health Index finds most vendors publish none of them. 5 of 143 clinical decision support vendors earn an A on Commercial Transparency. The structures a buyer meets are a per provider or per seat subscription, typically for reference and documentation adjacent tools; a volume based fee per study, encounter or evaluated case, typical of diagnostic models; and inclusion inside a platform or electronic record license the system already holds, which is the most common and the hardest to price, because the decision support line has no independent number to negotiate. Asking which of the three applies before asking for a figure is what makes the answer comparable across vendors.

Where can I find pricing for AI based decision support with vendor funded pilots?

Mostly in the contract rather than on a website, and the AI Health Index records how little of it is published. It grades every clinical decision support vendor on Commercial Transparency, where 5 of 143 earn an A and 21 reach an A or a B, verified as of October 22, 2026, so this category page is the fastest way to see which vendors state a pricing unit at all before you ask for a quote. Vendors often fund pilots in decision support because they need local validation data as much as the health system needs proof, which is why the pilot terms matter more than the pilot price. Settle three things in writing before a vendor funded pilot starts: the price and pricing unit that apply if the pilot converts, who owns the performance data the pilot produces, and whether the model or any patient data may be reused after the pilot ends. A pilot with no stated conversion price leaves the real negotiation until after the product is already embedded in the workflow.

How does the AI Health Index grade clinical decision support?

On fifteen capability axes, researched from public sources, with a verification date on every record and grades running A to D. A grade measures what an outside buyer can verify on that date rather than how good the product is, so a D records an absence far more often than a defect, and a vendor that publishes more is regraded with the change logged. No vendor pays for inclusion, for a grade or for placement. The index publishes no composite score for this category in particular, because a decision support product can be excellent clinically and unfit for a given health system on integration alone, and one number would hide exactly that.

Do vendors pay to appear in the AI Health Index clinical decision support category?

No. The AI Health Index is researched from public sources, no vendor pays for inclusion, for a grade or for placement, and every record carries the date it was last verified.

Head to Head

Clinical Decision Support comparisons

76 published

Comparisons are published only where the index assesses two vendors as direct competitors for the same buyer. Each carries a verdict, the buyer conditions that favor each side, and a graded side by side across all fifteen capability axes.

4baseCare vs Anterior→Abstractive Health vs Regard→Abstractive Health vs xCures→AccurKardia vs Ceribell→aetherAI vs Ibex Medical Analytics→aetherAI vs Modella AI→Aiberry vs Videra Health→Aidoc vs Harrison.ai→Aidoc vs Gleamer→Aidoc vs Heartflow→Aidoc vs Lunit→AITRICS VitalCare vs Bayesian Health→AITRICS VitalCare vs CLEW Medical→AITRICS VitalCare vs Healthplus.ai→Harrison.ai vs Behold.ai→Harrison.ai vs Gleamer→Harrison.ai vs Rayscape→ArteraAI vs DoMore Diagnostics→ArteraAI vs Nucs AI→ASCO Guidelines Assistant vs DynaMed→Atropos Health vs Triomics→Atropos Health vs Vera Health→Avo vs Glass Health→Avo vs MedPearl→Avo vs OpenEvidence→AZmed vs Infervision→AZmed vs Rayscape→Azra AI vs RhythmX AI→Bayesian Health vs Cytovale IntelliSep→Bayesian Health vs Healthplus.ai→Bayesian Health vs VUNO→Behold.ai vs Gleamer→Behold.ai vs Qure AI→CaryHealth Clair vs OpenEvidence→CaryHealth Clair vs Rejoy Health→Cleerly vs Nanox.AI→CLEW Medical vs Luminare→Cohere Health vs Xsolis→Curbside Health vs MedPearl→DoseMeRx vs PrecisePK→Doximity Ask vs Vera Health→Dyania Health vs Triomics→DynaMed vs Medwise.ai→DynaMed vs Micromedex→FDB (First Databank) vs InpharmD→FDB (First Databank) vs Synapse Medicine→Glass Health vs OpenEvidence→Glass Health vs Vera Health→Gleamer vs Rayscape→GuideAI Health vs Nucs AI→Healthplus.ai vs Luminare→Heartflow vs Viz.ai→Infermedica vs Ubie→Infermedica vs XUND→Infervision vs Lunit→Infervision vs Qure AI→InsightRX vs PrecisePK→Lucem Health vs Oatmeal Health→Lunit vs Oatmeal Health→Lunit vs Viz.ai→MedAware vs TheraDoc→MedAware vs VigiLanz→Medwise.ai vs OpenEvidence→Mendel vs Triomics→Milvue vs Rayscape→Nanox.AI vs Riverain Technologies→Navina vs RAAPID→Oxipit vs Qure AI→Paradigm Health vs Triomics→Qure AI vs Rayscape→Qure AI vs Riverain Technologies→RAAPID vs Xsolis→RapidAI vs Viz.ai→Rayscape vs Riverain Technologies→TheraDoc vs TransformativeMed→TransformativeMed vs VigiLanz→