Paradigm Health vs Triomics (2026)
Two trial matching platforms with real evidence, split by scope and by what comes with the software. Paradigm reasons over full text notes inside the provider record system across a large named network spanning dozens of states, and crucially it supplies recruitment staff alongside the technology, which is usually the difference between a match list and an enrolled patient. Triomics is oncology only and better evidenced for it, with peer reviewed validation, every match traced back to the pathology and biomarker behind it, and the deepest workflow integration in this category. For a cancer centre with coordinators already in place, Triomics does the harder reasoning and shows its working. For a site that has trials but nobody free to work them, Paradigm is selling the missing capacity as much as the software.
- It deploys inside the provider record system and reasons over full text notes with language models rather than structured prefilters, and published a direct comparison making that case.
- The network is specific and verifiable across dozens of states and well over a hundred provider organisations including designated cancer centres.
- It pairs software with recruitment staff, so a site is not left to convert a match list into enrolments on its own.
- It is oncology tuned rather than disease agnostic, which matters because the decisive eligibility detail usually sits in pathology and biomarker text.
- Peer reviewed validation in a recognised digital medicine journal is the strongest evidence position in this category.
- Every match traces back to the pathology, biomarker and note that produced it, and the output lands where the oncology team already works.
This comparison is published by AI Health Index, an independent research platform that compares healthcare AI vendors objectively. Paradigm Health and Triomics are each graded against the same capability taxonomy, from each vendor's own public materials and the regulatory record, under the AI Health Index verification standard. No vendor pays for placement, and no vendor has reviewed this page. How this evidence is graded
Plain facts
| Fact | Paradigm Health | Triomics |
|---|---|---|
| Primary category | Clinical Trials AI | Clinical Trials AI |
| Founded | 2021 | 2021 |
| Headquarters | Boston, Massachusetts, United States | San Francisco, California |
| Website | paradigmhealth.ai | triomics.com |
Side by Side
Each record in one paragraph
Written to be quoted whole. Each paragraph states what the AI Health Index verified about the vendor, with the caveats attached. Generated from this pair’s live capability grades, so it moves when a grade moves.
The AI Health Index awards Paradigm Health its top capability grade on several axes, including AI Centrality, Autonomy and Oversight Model and Clinical and Operational Evidence. Set against Triomics, Paradigm Health does not grade higher on any scored axis, though the two are level on several axes, including AI Centrality, Autonomy and Oversight Model and Clinical and Operational Evidence. Grades reflect evidence the AI Health Index could verify at the last review, so a low grade records disclosure the vendor has not published rather than a capability it has been shown to lack.
Source: AI Health Index, August 2026
The AI Health Index awards Triomics its top capability grade on several axes, including AI Centrality, Autonomy and Oversight Model and Model and Technology Transparency. Set against Paradigm Health, Triomics grades higher on several axes, including Model and Technology Transparency, Model Supply Chain Disclosure and AI Safety and PHI Stewardship. Grades reflect evidence the AI Health Index could verify at the last review, so a low grade records disclosure the vendor has not published rather than a capability it has been shown to lack.
Source: AI Health Index, August 2026
Questions buyers ask
Should we choose Paradigm Health or Triomics?
The AI Health Index grades Triomics higher than Paradigm Health on every axis that separates them, several axes, including Model and Technology Transparency, Model Supply Chain Disclosure and AI Safety and PHI Stewardship. Paradigm Health does not grade higher on any scored axis.
Where do Paradigm Health and Triomics differ most?
The widest separation the AI Health Index records between Paradigm Health and Triomics is on Model and Technology Transparency, where Paradigm Health grades B and Triomics grades A. That axis sits in the AI Capability group, so it should carry the most weight for a buyer whose binding constraint is how much of the work the model itself is trusted to do.
Where do Paradigm Health and Triomics grade the same?
The AI Health Index grades Paradigm Health and Triomics the same on several axes, including AI Centrality, Autonomy and Oversight Model and Clinical and Operational Evidence. Neither holds an advantage the index can evidence on those axes, so they should not carry weight in a selection between these two.
Related comparisons
Other published head to head assessments involving these vendors or their closest peers. The full set for this category is on the Clinical Decision Support page.
Both should be asked for the false negative rate on eligibility screening, which neither publishes, since an eligible patient who never surfaced is invisible in every metric either reports. Trial matching also inherits documentation bias: patients with thin or fragmented records match less often regardless of eligibility, and that population overlaps with the one trials already under enrol.
Neither publishes a security attestation, and Paradigm publishes nothing on business associate status. Neither publishes pricing, and the commercial shapes differ, since one bundles recruitment staffing and the other does not.