Asimily vs Cylera (2026)
Both began in hospitals and now sell into other sectors as well. Asimily builds its inventory with an on site Edge appliance, using passive monitoring and safe queries. It ranks each vulnerability by how likely it is to be exploited on that device in that network. It also checks a device's risk before purchase. Cylera collects device data passively, without agents. It builds virtual copies of devices from their traffic and runs vulnerability tests against those instead of the live equipment. A policy generator writes segmentation rules, and utilization analytics serve biomedical engineering. Choose Asimily for exploit ranking, pre purchase checks and a stated hosting model; choose Cylera to test vulnerabilities on emulated copies of devices.
- Vulnerabilities should be ranked by exploit likelihood on your own devices and network.
- A device's risk should be checked before you buy it.
- Your security review needs a stated hosting model and a SOC 2 Type II report.
- Vulnerability tests should run on emulated devices, not live ones.
- New devices should be enrolled into segmentation policy automatically.
- You report against the NHS Data Security and Protection Toolkit as well as US rules.
This comparison is published by AI Health Index, an independent research platform that compares healthcare AI vendors objectively. Asimily and Cylera are each graded against the same capability taxonomy, from each vendor's own public materials and the regulatory record, under the AI Health Index verification standard. No vendor pays for placement, and no vendor has reviewed this page. How this evidence is graded
Plain facts
| Fact | Asimily | Cylera |
|---|---|---|
| Primary category | Healthcare Cybersecurity | Healthcare Cybersecurity |
| Founded | 2017 | Not recorded |
| Headquarters | Sunnyvale, California, United States | New York, New York, United States |
| Website | asimily.com | cylera.com |
Side by Side
Select any grade to read the note behind it.
Each vendor in one paragraph
Written to be quoted whole. Each paragraph opens the AI Health Index profile of the vendor: what the product is, who buys it and what it does.
Asimily sells an exposure management platform for connected devices (medical devices, IoT, OT and IT endpoints), with hospitals and health systems as its founding market and customers in manufacturing, energy, finance and other sectors.
Source: AI Health Index, September 2026
Cylera sells an IoT asset intelligence and security platform that began in hospitals and now also serves finance, higher education, transportation, manufacturing and energy. Collection is agentless and passive, extracting device context from known and unknown protocols. Its distinguishing technique is network traffic emulation: the platform builds virtual stand-ins for devices from their traffic and probes those instead of the live equipment, so vulnerability testing never touches a device in clinical use.
Source: AI Health Index, September 2026
Questions buyers ask
How do Asimily and Cylera work with the EHR?
For Asimily, the integrations page describes two-way sync with CMMS and CMDB systems, automatic work orders for anomalies and vulnerabilities, NAC-driven segmentation, SIEM syslog export, vulnerability scanner, DHCP and IPAM, IAM and RTLS feeds, and shows Accruent, TRIMEDX, TruAsset, Cisco, Palo Alto Networks, CrowdStrike, Arista and Axonius.
With Cylera, integration pages and solution briefs cover Cisco ISE, Prime and DNA Center, Aruba ClearPass, Extreme NAC, Forescout, Illumio, Check Point, SonicWall, Microsoft Sentinel, Google Chronicle, IBM QRadar, Splunk, Rapid7 InsightVM, ServiceNow, Nuvolo and Integra e-Quip. No named hospital is shown running a two-way CMMS integration. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 30, 2026. No vendor pays for placement.
How are Asimily and Cylera priced and sold?
In Asimily's case, the platform is sold through demos and channel partners, with ProSecure pre-purchase lookups and the CMMS integrations as named capabilities.
For Cylera, the platform is sold through demos, a product tour and channel partners in North America, the UK and Europe. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 30, 2026. No vendor pays for placement.
How do Asimily and Cylera handle patient data?
With Asimily, the product security page says neither PII nor ePHI is transmitted out of the on-site Edge appliance, data processed at the Edge is not written to disk, in-memory data is deleted after processing, cloud data stays in the country of origin, nothing is shared with third parties without customer authorization, and each customer runs on dedicated instances.
In Cylera's case, the privacy statements cover website visitors only. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 30, 2026. No vendor pays for placement.
What evidence is published for Asimily and Cylera?
For Asimily, the home page claims more than 10,000 high-risk vulnerabilities removed in three months. KLAS rated Asimily first in its 2026 Healthcare IoT Security report at 96.6, a satisfaction measure.
St. Luke's University Health Network's CISO is quoted, case studies are listed for RWJBarnabas Health, St. Luke's and Morecambe Bay (behind download forms), the American Hospital Association selected Cylera as a preferred cybersecurity provider in April 2021, and an analyst SPARK Matrix report is offered. The home page lists improvements in discovery, risk score accuracy and alert workload without a figure. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 30, 2026. No vendor pays for placement.
Related comparisons
Other published head to head assessments involving these vendors or their closest peers. The full set for this category is on the Healthcare Cybersecurity page.
Both records were reviewed on this site in September 2026. Neither publishes a price. Cylera publishes no security attestation, product privacy terms, business associate position or hosting model. Its privacy statements cover the website, not the product. Asimily states SOC 2 Type II and C5, with the report on request. Asimily says patient data never leaves its Edge appliance. It states no business associate position. Cylera enrolls new devices into segmentation policy automatically, and no approval step is published. Asimily's customer figures, such as 98 percent NIST compliance at MemorialCare, are published without method. Cylera's case studies sit behind download forms. Its home page gives no figures. Both publish rank claims about themselves, which this page does not rely on.
Ask Cylera how closely an emulated device matches the real one, and ask Asimily how its exploit ranking is validated.