Healthcare Cybersecurity
C

Cylera

Cylera sells an IoT asset intelligence and security platform that began in hospitals and now also serves finance, higher education, transportation, manufacturing and energy. Collection is agentless and passive, extracting device context from known and unknown protocols. Its distinguishing technique is network traffic emulation: the platform builds virtual stand-ins for devices from their traffic and probes those instead of the live equipment, so vulnerability testing never touches a device in clinical use. Machine learning drives threat prioritization and alert reduction.

The platform covers discovery and inventory, vulnerability and risk management, threat detection and response, a segmentation policy generator with automatic enrollment of new devices, device utilization analytics for biomedical engineering, and US and UK compliance reporting, including support for the NHS Data Security and Protection Toolkit. Named integrations include Cisco ISE, Prime and DNA Center, Aruba ClearPass, Extreme NAC, Forescout, Illumio, Check Point, Microsoft Sentinel, Splunk, IBM QRadar, Rapid7, ServiceNow, Nuvolo and Integra e-Quip. The American Hospital Association selected it as a preferred cybersecurity provider in 2021, and St. Luke's, RWJBarnabas and NHS trusts appear as customers.

The site publishes no security attestation, product privacy terms, business associate position, hosting model or price; its privacy statements and terms cover the website only. Ask for all of these, and for how faithfully an emulated device matches the real one, before a security review.

AI Health Index verifiedSeptember 29, 2026
Compare Cylera with other vendors
Founded
—
Headquarters
New York, New York, United States
Website
cylera.com
Categories
healthcare-cybersecurity
Indexed Products
Cylera platform (IoT asset intelligence and security), Network traffic emulation for out-of-band vulnerability testing, Segmentation policy generator, Device utilization analytics
Buyer Segments
Hospitals and health networks, NHS trusts, Biomedical engineering and IT security teams, Financial services, higher education, transportation, manufacturing and energy organizations
Assessment

Capability Axes

An AI Health Index grade measures what a buyer can verify from public sources on the date shown. It is not a rating of how good the product is. A vendor can build an excellent system and grade low on an axis because it publishes nothing an outsider can check. How grades read

AI Capability
BB on AI CentralityThe model is the engine of a core module. The platform carries other value, but this capability does not exist without it.
Vendor Published

Models support detection and prioritization inside a wider platform. Cylera says its platform is powered by machine learning insights, applies machine learning to threat prioritization and alert reduction, and uses network traffic emulation to build virtual stand-ins for devices so they can be probed without touching the real equipment. Asset discovery and inventory, the segmentation policy generator, device utilization analytics, compliance reporting and its NAC, SIEM and CMMS integrations would still stand without the models.

CC on Autonomy and Oversight ModelAutonomy is claimed and oversight is asserted without a mechanism. Human in the loop appears as a phrase rather than a described control.
Vendor Published

Automation is described and the approval step is not. The segmentation policy generator writes rules, auto-enrolls new IoT devices into policy and monitors it, with enforcement through NAC and firewall integrations such as Cisco ISE; probing is done against emulated devices rather than live ones. Nothing published says which policy changes wait for a person, how auto-enrollment of a misidentified clinical device is caught, or how a change is rolled back.

BB on Model and Technology TransparencyThe approach or the suppliers are named without the version and update discipline behind them. Naming a supplier is the entry to this band both here and on Model Supply Chain Disclosure, which ask different questions of the same disclosure: who receives the data, and what produces the output.
Vendor Published

The approach is explained, and the models behind it are not. Cylera explains why it emulates devices: fragile medical equipment cannot be actively scanned in use, passive monitoring alone cannot test for vulnerabilities, so the platform builds virtual stand-ins from traffic and probes those, extracting context from known and unknown protocols without depending on protocol decoder libraries. Machine learning drives prioritization and alert reduction. No model, training data, version or accuracy figure is published.

CC on Model Supply Chain DisclosureThe architecture is described and no model provider is named. Naming a hosting provider alone does not lift a record out of this band. Record the host in the note, because it matters for residency and breach scope, and grade on the model layer, which is the question this axis is named for.
Vendor Published

The architecture is described and no party is named. Collection, emulation and machine learning are described as Cylera's own, but no hosting provider, model provider or subprocessor list is published, and nothing states where captured traffic and device emulations are kept.

CC on Clinical and Operational EvidenceNamed customers, or vendor reported percentages with no method, denominator or reference standard. Scale of use is recorded here and is not treated as evidence of benefit.
Vendor Published

Named customers without published results. St. Luke's University Health Network's CISO is quoted, case studies are listed for RWJBarnabas Health, St. Luke's and Morecambe Bay (behind download forms), the American Hospital Association selected Cylera as a preferred cybersecurity provider in April 2021, and an analyst SPARK Matrix report is offered. The home page lists improvements in discovery, risk score accuracy and alert workload without a figure.

DD on AI Safety and PHI StewardshipNothing published on how protected information moves through the system.
Vendor Published

Nothing published on how customer data moves through the product. Collection is agentless and passive, and building an emulated device means capturing and reconstructing its network communications, but no page states what traffic is retained, for how long, where it is stored, whether PHI in device payloads is handled, or whether one hospital's data informs emulations or models for others. The privacy statements cover website visitors only.

Regulatory and Compliance
DD on HIPAA and BAA PostureNo statement of status and no privacy document that reaches the product. Both halves are absent at this grade: a service level privacy document on its own lifts a vendor to the band above even where no status is stated. A website privacy notice, including one that says it does not cover customer data, does not reach the product, so a vendor whose only document is that notice and who states no status grades here.
Vendor Published

No statement of status and no privacy document that reaches the product. Cylera publishes HIPAA and UK Data Security and Protection Toolkit material about customers' own compliance, but no page states business associate status, offers an agreement, or says the platform does not handle PHI, and the US privacy statement and terms of use cover the website only. Clinical network traffic can carry PHI.

DD on Security Certifications and Trust CenterControls are asserted with nothing independent behind them, or nothing is published. Read the note before concluding anything: this is the grade most often corrected on a second pass, because assurance material frequently sits on a parent domain or inside an old announcement rather than on the product pages.
Vendor Published

No independent assurance is offered. The site has no trust center, security page or certification claim, and no SOC 2 or ISO 27001 statement from the company appears elsewhere. The product holds a map of every connected device in a hospital and emulations of how they communicate, and no penetration test results are published either.

BB on FDA and Regulatory StatusThe pathway is stated and in progress, or a clearance is named without the vintage and scope a buyer needs to match it to the product on offer.
Vendor Published

No device claim, with healthcare compliance work named. The platform is security software without a clearance and needs none. Cylera publishes separate US and UK healthcare compliance pages, supports the NHS Data Security and Protection Toolkit, and was selected by the American Hospital Association as a preferred provider in 2021; nothing addresses FDA device recalls or manufacturer disclosure statements, and no page states its own regulatory position.

CC on AI Governance and Bias DisclosureResponsible artificial intelligence is committed to in policy language with no evaluation behind it. Most of the index sits here.
Vendor Published

Nothing evaluates the models. Machine learning alert reduction and risk scoring are presented as core capabilities, and the site calls the platform the most accurate available, but no accuracy, precision, false negative rate or governance framework is published, and nothing says whether one customer's device data informs models used for others. Alert reduction without a false negative rate cannot be judged on safety grounds.

DD on AI Liability and RecourseNothing published on what happens when the system is wrong.
Vendor Published

The company says nothing about what happens when the system is wrong. It gives no detection or false positive rate and no measure of how faithfully an emulated device matches the real one. Generated policies come with no described review before commit step or audit trail, and there is no warranty, indemnity or remediation commitment; the only terms published cover the website and disclaim accuracy. The vulnerability findings rest on the emulation, yet how its fidelity is validated, and for which device classes it works poorly, goes undescribed.

Integration and Deployment
BB on EHR and Interoperability DepthNamed systems with read access or one directional writing, or standards support with named deployments behind it.
Vendor Published

It does not connect to the clinical record; its integrations with the hospital's security and clinical engineering systems are named without production evidence. Integration pages and solution briefs cover Cisco ISE, Prime and DNA Center, Aruba ClearPass, Extreme NAC, Forescout, Illumio, Check Point, SonicWall, Microsoft Sentinel, Google Chronicle, IBM QRadar, Splunk, Rapid7 InsightVM, ServiceNow, Nuvolo and Integra e-Quip. No named hospital is shown running a two-way CMMS integration.

DD on Deployment Model and Data ResidencyNothing published about where the system runs or where the data rests.
Vendor Published

Nothing published about where the system runs or where the data rests. The platform is described as agentless and passive, with probing done against emulated devices and a central console for multi-site networks, but no page says whether it is cloud hosted or on premises, which provider or region holds customer data, or how tenants are separated.

Commercial
CC on Commercial TransparencyNo price is published and the posture is discoverable: a buyer can establish how the product is sold and what drives the cost before contacting the vendor. Most of the index sits here.
Vendor Published

No price is published, and the sales route is discoverable. The platform is sold through demos, a product tour and channel partners in North America, the UK and Europe. No unit of charge or tier is published.

BB on Setting and Specialty CoverageCoverage is named with validation behind part of it.
Vendor Published

Healthcare settings are named, with results behind download forms. The platform covers medical devices, OT and IoT for hospitals and health networks in North America and Europe, with roles for biomedical engineering, IT and security, and it now also sells to finance, higher education, transportation, manufacturing and energy. Named hospital customers (St. Luke's, RWJBarnabas, Morecambe Bay, Dartford and Gravesham NHS Trust) appear in quotes and gated case studies.

Alternatives

Alternatives to Cylera

Vendors in the same categories as Cylera whose graded profiles look most alike, with a line on what each product does.

Similar is not the same, so check that each one does the job you need. No vendor pays for placement.

Haystack iS is iatricSystems' patient privacy monitoring software for hospitals and health systems, formerly Security Audit Manager.

Medcrypt sells cybersecurity compliance software and services to medical device manufacturers rather than to hospitals.

Finite State sells a product security platform to makers of connected devices, including medical device manufacturers, automotive, energy, industrial and government suppliers.

SPHER monitors access to patient information in healthcare applications.

Sternum sells embedded security that device manufacturers build into their own products, medical devices among them.

Medication and compliance intelligence company whose two surveillance products watch hospital staff for insider risk: ControlCheck, formerly Bluesight for Controlled Substances, for drug…

Ordered by how closely the graded profiles match across the fifteen axes, inside the same categories. See how each axis is graded in the methodology.

Comparisons

Compared With

Each comparison carries a written verdict, the buyer conditions that favor each vendor, and a graded side by side. Pairs that cross a category boundary are grouped separately, and their verdicts state where the boundary sits rather than manufacturing a head to head.

Commercial

Pricing

Vendor-published figures are labeled as such. Figures labeled “Estimated” are derived from third-party sources and have not been confirmed by the vendor.

Entry Price Pricing Basis BAA Tier Implementation Source
Not published
Not published. Sold through demos, a product tour and channel partners. Not published. No business associate status or agreement is stated. Not published. Vendor Published

No price, tier or unit of charge is published.

Three things to settle. The licensing unit, since per device, per bed and per site pricing behave very differently for a multi-hospital network. Whether the NAC, SIEM and CMMS integrations are in the base license. And a proof of value on your own device fleet, including how well the emulated devices match the real ones, before committing.