Overjet vs Pearl (2026)
Dental AI's head to head splits on what the algorithm is for. Overjet's distinction is measurement and the payer side: it quantifies caries and periodontal bone loss rather than only flagging them, and it sells a separate claims review product to dental insurers, meaning the same company's AI can sit chairside with the dentist and inside the payer reviewing the claim. Pearl's distinction is detection breadth and reach: Second Opinion highlights up to 18 finding types per radiograph, Second Opinion 3D extends to CBCT, making Pearl by its own account the first dental AI cleared for both 2D and 3D analysis, with pediatric coverage from age four and reported clearance in 120 countries. If your failure mode is disputes over what the image shows and what insurance will accept, start with Overjet. If your failure mode is findings walking out the door undetected across every image type you shoot, start with Pearl. Both hold FDA clearances; neither publishes pricing.
- Quantification over flagging: FDA cleared detection and measurement claims covering caries and periodontal bone loss, with visual overlays presented chairside in real time.
- You want alignment with the payer's reviewer: a separate claims review product used on the dental insurer side, so clinical documentation and claim review can run on the same analytical basis.
- Bone loss numbers, not just highlights: quantified periodontal measurements support perio diagnosis where a detection only overlay cannot.
- Breadth per image decides it: up to 18 finding types per radiograph across bitewing, periapical, and panoramic film, including caries, bone loss, calculus, periapical radiolucencies, and defective restoration margins.
- You shoot cone beam CT: Second Opinion 3D extends the platform to CBCT, per the company the first dental AI with FDA clearance for both 2D and 3D radiologic analysis, plus pediatric caries detection from age four.
- The study evidence is on the record: the panoramic clearance was supported by a standalone performance study and a fully crossed multi reader multi case study, and a published study reported operator diagnostic accuracy rising from 82 to 98 percent with the tool.
This comparison is published by AI Health Index, an independent research platform that compares healthcare AI vendors objectively. Overjet and Pearl are each graded against the same capability taxonomy, from each vendor's own public materials and the regulatory record, under the AI Health Index verification standard. No vendor pays for placement, and no vendor has reviewed this page. How this evidence is graded
Plain facts
| Fact | Overjet | Pearl |
|---|---|---|
| Primary category | Radiology & Imaging AI | Radiology & Imaging AI |
| Founded | 2018 | 2019 |
| Headquarters | Boston, Massachusetts, United States | West Hollywood, California |
| Website | overjet.com | hellopearl.com |
Side by Side
Select any grade to read the note behind it.
Product updates
The latest logged changes from each vendor, newest first, each linked to its source.
Overjet
-
Regulatory / FDA
Overjet received FDA clearance for its IRIS Real-time Image Quality Checking system.
Source
Pearl
-
Regulatory / FDA
Pearl received FDA clearance extending Second Opinion to panoramic radiographs, covering detection of suspected caries, periapical radiolucencies, and impacted third molars.
Source
Each vendor in one paragraph
Written to be quoted whole. Each paragraph opens the AI Health Index profile of the vendor: what the product is, who buys it and what it does.
Overjet is a dental AI company that analyzes radiographs in real time, detecting and outlining caries, periodontal bone loss, calculus and periapical radiolucency with overlays the dentist reviews chairside. Each function carries its own FDA clearance, eight in all from 2021 to 2026, including caries detection on bitewing and periapical radiographs (K222746), charting, image enhancement, cone beam CT (K251514, December 2025) and the IRIS imaging system (K253930, April 2026).
Source: AI Health Index, September 2026
Dental AI for radiographic pathology detection. Second Opinion analyzes bitewing, periapical and panoramic radiographs in real time chairside, highlighting findings such as caries, bone loss, calculus, periapical radiolucencies and defective restoration margins, and Second Opinion 3D extends it to CBCT.
Source: AI Health Index, September 2026
Questions buyers ask
How much do Overjet and Pearl leave to the clinician?
Overjet Caries Assist is cleared as a concurrent read computer aided detection device (K222746): it outlines or fills suspected lesions on the radiograph the dentist is already reading, and the dentist reviews and can edit them, so the output is inherently reviewable against the clinician's own read.
With Pearl, the clinician can toggle detection types, remove a detection the model got wrong and add one it missed, and the product states its own limitation on bone level measurement, that image angulation affects accuracy. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 28, 2026. No vendor pays for placement.
Related comparisons
Other published head to head assessments involving these vendors or their closest peers.
Pearl's 120 country clearance figure and the 82 to 98 percent accuracy study are vendor published; the multi reader multi case study supported a regulatory clearance. Overjet's payer side claims review product means its AI can appear on both sides of a dental claim; practices should understand which of their insurers use it. Neither vendor publishes pricing. On security, Overjet's trust center names a HITRUST certification without the report, and Pearl supplies a SOC 2 Type II report on request; neither report can be opened without asking.