UpToDate alternatives and competitors
The closest alternatives to UpToDate are Micromedex, ClinicalKey AI, OpenEvidence and Vera Health.
UpToDate is the clinical reference and decision support product of Wolters Kluwer Health, written by more than 7,600 physician authors and editors and used by more than three million clinicians.
10 alternatives to UpToDate
What each product does, with its price as the vendor publishes it.
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Micromedex is Merative's drug and toxicology reference for clinicians, pharmacists, poison centers and health plans. Merative was formed in 2022 when Francisco Partners bought IBM's Watson Health assets, and Micromedex now has its own product site.
Price: No published price
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ClinicalKey AI is a generative clinical decision support layer built on ClinicalKey, Elsevier Health's point of care content platform.
Price: Not published; 90 day free trial for clinicians, one year free for US and Canadian medical students
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AI medical search and clinical decision support used at the point of care, free to verified United States and Canadian clinicians and funded by pharmaceutical and medical device advertising shown inside the product, with enterprise deployments embedded in the electronic health record at…
Price: Free for verified clinicians
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Clinical evidence search engine for licensed clinicians, operated by Veracity-Health Inc., a Delaware corporation with a San Francisco address, and free to verified clinicians and trainees with unlimited searches.
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Generative chat interface over the American Society of Clinical Oncology's own library of clinical practice guidelines, announced in May 2025 and developed by ASCO and Google Cloud on the Vertex AI platform with Gemini models.
Price: No separate charge; included with ASCO membership (annual dues $0 to $695 by role and country)
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DynaMed is the point of care disease reference from EBSCO Clinical Decisions, part of EBSCO Information Services, based in Ipswich, Massachusetts.
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AMBOSS AI Mode Clinical Care answers medical questions with short summaries linked to selected sources. It draws on the edited AMBOSS library, US clinical guidelines and a drug database, adapting the presentation to a clinician's specialty and answering in the language of the question.
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Real world evidence generation, spun out of Stanford's Green Button project in 2020 and built to answer the question a clinician actually has at the bedside when no trial covers their specific patient.
Price: No published price
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UpToDate Lexidrug, formerly Lexicomp, is the drug reference Wolters Kluwer Health sells to pharmacists and prescribers.
Price: No published price
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Doximity Ask, formerly Doximity GPT, is the clinical AI assistant inside Doximity's professional network, whose members include more than 85 percent of US doctors.
More UpToDate comparisons
Side by side comparisons of UpToDate with products not listed above.
UpToDate alternatives, answered
What are the best alternatives to UpToDate?
The closest alternatives to UpToDate are Micromedex, ClinicalKey AI, OpenEvidence, Vera Health and ASCO Guidelines Assistant. Micromedex is Merative's drug and toxicology reference for clinicians, pharmacists, poison centers and health plans. ClinicalKey AI is a generative clinical decision support layer built on ClinicalKey, Elsevier Health's point of care content platform. Clinical evidence search engine for licensed clinicians, operated by Veracity-Health Inc., a Delaware corporation with a San Francisco address, and free to verified clinicians and trainees with unlimited searches.
Who are UpToDate's competitors?
UpToDate's competitors in the Clinical Reference & Evidence category include Micromedex, ClinicalKey AI, OpenEvidence, Vera Health, ASCO Guidelines Assistant and DynaMed.