Droxi vs MarianaAI (2026)
Both automate inbox work for practices, inside products of different size. Droxi Unbox closes normal lab results on the practice's settings and sends the patient a message the practice words. It puts refill requests on one screen and summarizes consult notes with each point linked to its source. Droxi Unlock supports enrollment in Advanced Primary Care Management. MarianaAI sells CARE, a platform of more than twenty modules that includes ambient documentation, autonomous medical coding, pre visit charting and inbox triage with auto drafted patient responses. The scribe's published workflow has the clinician review notes before they sync to the record. CARE is marketed on lifting revenue by 15 to 20 percent through risk adjustment and code capture. Choose Droxi for a focused inbox agent with a stated business associate agreement; choose MarianaAI for one contract spanning documentation, coding and inbox work.
- You want an inbox agent rather than a platform of modules.
- Consult notes should be summarized with each point linked to its source.
- A business associate agreement should be signed before any patient data is processed.
- You want documentation, coding and inbox triage from one vendor.
- Your record system is among the 50 or more MarianaAI says it integrates with.
- Patient responses should be drafted automatically from the inbox.
This comparison is published by AI Health Index, an independent research platform that compares healthcare AI vendors objectively. Droxi and MarianaAI are each graded against the same capability taxonomy, from each vendor's own public materials and the regulatory record, under the AI Health Index verification standard. No vendor pays for placement, and no vendor has reviewed this page. How this evidence is graded
Plain facts
| Fact | Droxi | MarianaAI |
|---|---|---|
| Primary category | Clinical Inbox & Messaging AI | Ambient Scribes |
| Founded | 2022 | Not recorded |
| Headquarters | Tel Aviv, Israel | San Jose, California |
| Website | droxi.com | marianaai.com |
Side by Side
Select any grade to read the note behind it.
Each vendor in one paragraph
Written to be quoted whole. Each paragraph opens the AI Health Index profile of the vendor: what the product is, who buys it and what it does.
Droxi Digital Health sells AI agents for the administrative side of primary care, working inside the electronic health record rather than as a separate application. The company was founded in 2022 by Gadi Shenhar (CEO) and Raveh Ben Simon (CTO), is headquartered in Tel Aviv, and names Drive Capital, Verissimo and AirAngels as backers.
Source: AI Health Index, September 2026
MarianaAI, based in San Jose, California, describes itself as a research lab building healthcare AI models, delivered through CARE, which stands for Comprehensive Automation and Revenue Enhancement. Ambient documentation is one module among more than twenty, alongside autonomous medical coding, pre visit charting, order management, CDI compliance, inbox triage with auto drafted patient responses, insurance coverage checks and a MarianaGPT assistant, integrated with a claimed 50 or more EHRs and reachable in the record, in browsers and on mobile.
Source: AI Health Index, September 2026
Questions buyers ask
How much do Droxi and MarianaAI leave to the clinician?
Droxi publishes how much runs unattended: 38 percent of routine work handled automatically, illustrated in the FAQ by one clinic closing 172 of 455 lab review items in a single week. The terms add that AI-generated summaries and suggestions must be reviewed by qualified personnel before being relied upon.
With MarianaAI, the autonomous coding module is marketed with the statement that it works with absolutely no human in the loop, generating ICD-10, CPT and HCPCS codes within seconds of the encounter and before the next appointment. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 30, 2026. No vendor pays for placement.
Related comparisons
Other published head to head assessments involving these vendors or their closest peers. The full set for this category is on the Clinical Inbox & Messaging AI page.
Both records were reviewed on this site in September 2026. Neither publishes a price. Droxi closes some results and messages the patient with no clinician involved. It states no regulatory position on that. MarianaAI markets its coding module as working with "absolutely no human in the loop". It publishes no threshold or escalation path for that coding. MarianaAI's figures, including 10x return on investment and revenue up 15 to 20 percent, carry no denominator or method. Droxi's headline figures, 5.1 hours a week and a 51.9 percent cut in after hours work, name no site or method. MarianaAI's terms make its fees non refundable. They also reserve its right to use recordings and transcripts to improve its offerings. Droxi's FAQ says it signs a business associate agreement with every customer. MarianaAI's privacy policy states a business associate role, and the agreement itself is not published.
Ask MarianaAI whether a person reviews its auto drafted patient replies, and ask Droxi how often an auto closed result later needed a clinician.