Bayesian Health vs Epic Sepsis Model (2026)
Both detect sepsis early from the EHR, and they are bought differently. Bayesian Health, a Johns Hopkins spinout founded by Suchi Saria, sells machine learning models that read the record continuously and flag inpatients at rising risk, with workflows that prepare order sets and documentation for clinicians. Its sepsis module is FDA cleared, and further modules cover deterioration, readmissions and more. The Epic Sepsis Model is built into Epic's record, scoring adult emergency and hospitalized patients every 15 minutes against a threshold each health system sets. Epic states no regulatory position for it, and outside researchers have revalidated it. Choose Bayesian for a cleared sepsis model with the clinical workflow built around it; choose the Epic model if you run Epic and will manage the threshold yourself.
- You want a sepsis model that is FDA cleared and marketed within its clearance.
- Alerts should come with order sets and documentation ready for the clinician.
- You may add modules for deterioration or readmissions later.
- Your hospital runs Epic and wants the model already in the record.
- Independent revalidation matters to your committee.
- Your team will set and monitor the threshold.
This comparison is published by AI Health Index, an independent research platform that compares healthcare AI vendors objectively. Bayesian Health and Epic Sepsis Model are each graded against the same capability taxonomy, from each vendor's own public materials and the regulatory record, under the AI Health Index verification standard. No vendor pays for placement, and no vendor has reviewed this page. How this evidence is graded
Plain facts
| Fact | Bayesian Health | Epic Sepsis Model |
|---|---|---|
| Primary category | Inpatient Deterioration & Risk Monitoring | Inpatient Deterioration & Risk Monitoring |
| Founded | 2018 | 1979 |
| Headquarters | New York, New York, United States | Verona, Wisconsin, United States |
| Website | bayesianhealth.com | epic.com |
Side by Side
Select any grade to read the note behind it.
Product updates
The latest logged changes from each vendor, newest first, each linked to its source.
Bayesian Health
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Regulatory / FDA
CMS approved a New Technology Add-on Payment for Bayesian Health's FDA cleared continuous AI sepsis monitor, creating Medicare payment support for health systems running the platform.
Source
Each vendor in one paragraph
Written to be quoted whole. Each paragraph opens the AI Health Index profile of the vendor: what the product is, who buys it and what it does.
Bayesian Health, a Johns Hopkins spinout founded by Suchi Saria, sells a platform of machine learning models that read the EHR continuously and flag inpatients at rising risk, with workflows that prepare order sets and documentation for clinicians to act on. Its lead module detects sepsis early.
Source: AI Health Index, September 2026
The Epic Sepsis Model is the sepsis prediction model built into Epic's electronic health record. It scores adult emergency and hospitalized patients every 15 minutes and alerts clinicians when a score crosses the threshold each health system sets. Version 1 (2018) was a penalized logistic regression.
Source: AI Health Index, September 2026
Questions buyers ask
How do Bayesian Health and Epic Sepsis Model work with the EHR?
For Bayesian Health, the 510(k) summary calls the device's web application EHR agnostic and integrated into the EHR so clinicians see flags in their existing workflow, and the platform page says flags trigger workflows inside the EHR that tee up order sets, pathway steps and documentation.
The model reads vital signs, laboratory results, medication administration and other chart data directly from Epic every 15 minutes and returns its score and alerts into the clinician's workflow, with no interface or data feed to build. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 29, 2026. No vendor pays for placement.
How are Bayesian Health and Epic Sepsis Model priced and sold?
In Bayesian Health's case, the product is sold to health systems as an enterprise platform, by module, with implementation that tunes models to each site.
The model is available only to Epic customers, inside Epic, and is switched on by the health system; the Wong paper records Epic's figure of 95 organizations on version 2 and more than 100 still on version 1 in August 2025. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 29, 2026. No vendor pays for placement.
How do Bayesian Health and Epic Sepsis Model handle patient data?
With Bayesian Health, the company's privacy policy covers its marketing website. Nothing published states what patient data is retained, for how long, whether one health system's data develops models used by others, or who inside the company can reach identified records.
The model runs inside the health system's Epic environment and each site fine-tunes version 2 on its own historical inpatient data, as the independent validations describe the deployment, so no third party model provider receives patient data. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 29, 2026. No vendor pays for placement.
Which settings and specialties do Bayesian Health and Epic Sepsis Model cover?
For Bayesian Health, the cleared sepsis module covers adults 18 and over from emergency department presentation or admission through the stay in acute care, including observation units, general wards and intensive care, and its evidence spans five hospitals in the outcome study and four in the clearance study, academic, urban and suburban.
With Epic Sepsis Model, coverage is adults only, with no pediatric model. Performance varies widely by site, so the validated settings show where the model has been tested, not how it will perform at a new hospital. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 29, 2026. No vendor pays for placement.
Related comparisons
Other published head to head assessments involving these vendors or their closest peers. The full set for this category is on the Inpatient Deterioration & Risk Monitoring page.
Both records were reviewed on this site in September 2026. Neither publishes a price. Bayesian's clearance reports agreement and positive predictive value, but no lead time was found in what was read. Epic states no regulatory position for its model, and alert burden is left for each hospital to measure.
Ask both how many hours of warning a clinician gets, and how many alerts come with it.