AgileMD vs Epic Sepsis Model (2026)
A cleared device against an embedded feature, and the paperwork is the argument. eCART is FDA cleared Class II software with a named model class, a defined indication limited to hospitalised adult ward patients, more than fifty peer reviewed publications behind it and the first race stratified performance disclosure in this category. The Epic Sepsis Model is proprietary, has published no model description or subgroup analysis, operates under the decision support exclusions, and is running at hundreds of hospitals right now at no incremental procurement cost. Most health systems evaluating this are really asking whether to pay for something they already have a version of. The answer turns on what the free one is doing at your hospital, which almost nobody has measured, and on whether your quality committee is comfortable defending a model nobody outside the vendor can describe.
- The model is the cleared device and the filing says so, with the model class named and the cleared indication restricting use to hospitalised ward patients aged 18 and over, which is an explicit and unusual scope statement.
- More than fifty peer reviewed publications behind it since 2012, which is the deepest evidence base in this category and one of the deepest in the index.
- It published race stratified performance, the first vendor in this category to do so, which is the benchmark every other deterioration vendor should now be asked to match.
- No procurement at all. It runs inside the record system the hospital already licenses, with no new contract, integration project or data processor.
- The widest deployment of any product in this index, and the published evidence about it spans genuinely different hospital settings rather than one institution's experience.
- The privacy position is structurally strongest, since the model runs inside the existing record system under the existing agreement and no third party receives patient data.
This comparison is published by AI Health Index, an independent research platform that compares healthcare AI vendors objectively. AgileMD and Epic Sepsis Model are each graded against the same capability taxonomy, from each vendor's own public materials and the regulatory record, under the AI Health Index verification standard. No vendor pays for placement, and no vendor has reviewed this page. How this evidence is graded
Plain facts
| Fact | AgileMD | Epic Sepsis Model |
|---|---|---|
| Primary category | Inpatient Deterioration & Risk Monitoring | Inpatient Deterioration & Risk Monitoring |
| Founded | 2011 | 1979 |
| Headquarters | San Francisco, California | Verona, Wisconsin |
| Website | agilemd.com | epic.com |
Side by Side
Each record in one paragraph
Written to be quoted whole. Each paragraph states what the AI Health Index verified about the vendor, with the caveats attached. Generated from this pair’s live capability grades, so it moves when a grade moves.
The AI Health Index awards AgileMD its top capability grade on several axes, including AI Centrality, Autonomy and Oversight Model and Model and Technology Transparency. Set against Epic Sepsis Model, AgileMD grades higher on several axes, including AI Centrality, Autonomy and Oversight Model and Model and Technology Transparency. Grades reflect evidence the AI Health Index could verify at the last review, so a low grade records disclosure the vendor has not published rather than a capability it has been shown to lack.
Source: AI Health Index, August 2026
The AI Health Index awards Epic Sepsis Model its top capability grade on Clinical and Operational Evidence, EHR and Interoperability Depth and Setting and Specialty Coverage. Set against AgileMD, Epic Sepsis Model grades higher on several axes, including Model Supply Chain Disclosure, HIPAA and BAA Posture and EHR and Interoperability Depth. Its thinnest published disclosure sits on Model and Technology Transparency and AI Liability and Recourse. Grades reflect evidence the AI Health Index could verify at the last review, so a low grade records disclosure the vendor has not published rather than a capability it has been shown to lack.
Source: AI Health Index, August 2026
Questions buyers ask
Should we choose AgileMD or Epic Sepsis Model?
On the axes where the AI Health Index separates them, AgileMD grades higher on several axes, including AI Centrality, Autonomy and Oversight Model and Model and Technology Transparency, and Epic Sepsis Model grades higher on several axes, including Model Supply Chain Disclosure, HIPAA and BAA Posture and EHR and Interoperability Depth. AgileMD leads on the greater share of scored axes, but the split means the decision turns on which constraint is binding rather than on an overall winner.
Where do AgileMD and Epic Sepsis Model differ most?
The widest separation the AI Health Index records between AgileMD and Epic Sepsis Model is on Model and Technology Transparency, where AgileMD grades A and Epic Sepsis Model grades D. That axis sits in the AI Capability group, so it should carry the most weight for a buyer whose binding constraint is how much of the work the model itself is trusted to do.
Where do AgileMD and Epic Sepsis Model grade the same?
The AI Health Index grades AgileMD and Epic Sepsis Model the same on several axes, including Clinical and Operational Evidence, AI Safety and PHI Stewardship and Security Certifications and Trust Center. Neither holds an advantage the index can evidence on those axes, so they should not carry weight in a selection between these two.
What have AgileMD and Epic Sepsis Model not disclosed?
At the last review, at least one of AgileMD and Epic Sepsis Model published thin or absent detail on Model and Technology Transparency and AI Liability and Recourse. The AI Health Index treats an absent disclosure as a gap in the public record rather than a failure of the product, so these are the axes to get in writing during diligence instead of inferring from the grade.
Related comparisons
Other published head to head assessments involving these vendors or their closest peers. The full set for this category is on the Inpatient Deterioration & Risk Monitoring page.
The two products are not equivalent in regulatory status and that is the substance of this comparison. eCART holds a 510(k) clearance as Class II software with a defined indication and a named model class; the Epic Sepsis Model operates under the clinical decision support exclusions with no device authorisation, no published model description and no subgroup performance disclosure at a national deployment scale.
AgileMD's SOC 2 claim does not specify the type, which is the standing question this index puts to every unqualified attestation. Neither vendor publishes pricing, and Epic publishes no indication of whether the model is included in an existing licence or priced separately.