Healthcare Administrative Automation
P

Plenful

No code AI workflow automation for pharmacy and healthcare operations, with a center of gravity in 340B program compliance. The platform screens 340B eligible claims, uses language models to investigate unstructured EHR data for referral based savings, and automates rebate reporting, Maximum Fair Price reconciliation, intake, and prior authorization. Referral Agent, launched June 2026, is positioned by the company as the first AI agent purpose built for 340B referral capture. The vendor reports customers including Tampa General Hospital, Renown Health, and Salinas Valley Health, more than 100 healthcare organizations on the platform, and customer reported reductions in manual work of up to 97 percent. Founded by Joy Liu, previously an operator at a health system specialty pharmacy company. Raised a $50 million Series B in 2025.

Last VerifiedJuly 19, 2026
Founded
Headquarters
San Francisco, California
Website
www.plenful.com
Categories
healthcare-admin-automation, rcm-and-prior-auth
Indexed Products
340B Suite, Referral Agent, MFP Intelligence
Buyer Segments
Large IDN, Academic Medical Center, Community Health System
Assessment

Capability Axes

AI Capability
AI Centrality
B
Vendor Published

Language models do the substantive work of investigating unstructured EHR data for referral based 340B savings, and the vendor reports this raises review capacity by a large multiple. Held back from A because the platform is explicitly a no code workflow automation layer in which AI is one component alongside configurable rules and audit logic, and some of the value is orchestration rather than inference.

Autonomy and Oversight Model
B
Vendor Published

The vendor states the platform combines AI based automation with human oversight, and the 340B compliance context imposes an audit trail by regulation. Held back from A because the escalation and exception handling model is described in marketing terms rather than documented, and no published governance framework was retrieved.

Model and Technology Transparency
Not rated
Clinical and Operational Evidence
B
Vendor Published

Named customers including Tampa General Hospital, Renown Health, and Salinas Valley Health, with more than 100 healthcare organizations reported on the platform and specific customer attributed figures such as up to 97 percent reductions in manual work and over 50 staff hours a day saved. Held back from A because the figures are customer testimonial rather than measured against a stated baseline methodology.

AI Safety and PHI Stewardship
Not rated
Regulatory and Compliance
HIPAA and BAA Posture
Not rated
Security Certifications and Trust Center
Not rated
FDA and Regulatory Status
Not rated
AI Governance and Bias Disclosure
Not rated
Integration and Deployment
EHR and Interoperability Depth
Not rated
Deployment Model and Data Residency
Not rated
Commercial
Commercial Transparency
Not Rated
Vendor Published

No public pricing. Contact the vendor. Enterprise agreements with health systems and pharmacy organizations; no published rate card.

Setting and Specialty Coverage
A
Vendor Published

Precisely scoped and honestly bounded: pharmacy and healthcare administrative operations, centered on 340B covered entities, specialty and long term care pharmacy, and health system pharmacy departments. The vendor does not claim clinical scope.

Public Record

Announced Deployments

Publicly announced health system deployments and partnerships. This is a record of announcements, not an assessment of deployment success or scale.

Salinas Valley Health
Plenful 340B auditing and compliance
Renown Health
Plenful workflow automation across pharmacy operations
Tampa General Hospital
Plenful workflow automation across pharmacy operations
Commercial

Pricing

Vendor-published figures are labeled as such. Figures labeled “Estimated” are derived from third-party sources and have not been confirmed by the vendor.

Entry Price Pricing Basis BAA Tier Implementation Source
Contact the vendor
Enterprise agreements scoped by use case Vendor Published

Enterprise agreements with health systems and pharmacy organizations, typically scoped by use case. The vendor markets savings recapture in 340B referral claims, which means part of the economics is framed as recovered revenue rather than cost. No rate card published.

AI Health Index

An independent reference for evaluating AI vendors in healthcare. No vendor pays for inclusion, placement, or rating.

Index Status
Last index update
July 19, 2026
The AI Health Index is an editorial reference, not a regulatory body. Vendor data is verified against published sources and public regulatory filings. Figures labeled “Estimated” have not been confirmed by the vendor. See the Methodology page for evaluation standards and limitations.
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