Hyro vs Infermedica (2026)
Both sit at the front door of a health system, doing different jobs. Hyro runs conversational agents across the call center, website, text and mobile apps for scheduling, provider search, refills, MyChart password resets and help desk requests, answering from sources the health system approves and handing complex calls to staff. Infermedica provides the clinical triage: probabilistic models over a physician curated knowledge base take a patient from a symptom to a recommended level of care, under EU medical device certification and a stated US position, with a published five level scale. They can work together. Choose Hyro to take routine requests off the phones; choose Infermedica when patients need to know how urgently to seek care.
- Routine requests are swamping the call center.
- The agent should work across web, text and mobile as well as the phone.
- Answers should come only from sources your health system approves.
- Patients need to be sent to the right level of care from their symptoms.
- A published regulatory position matters to your compliance team.
- Triage should plug into your own app, portal or nurse line.
This comparison is published by AI Health Index, an independent research platform that compares healthcare AI vendors objectively. Hyro and Infermedica are each graded against the same capability taxonomy, from each vendor's own public materials and the regulatory record, under the AI Health Index verification standard. No vendor pays for placement, and no vendor has reviewed this page. How this evidence is graded
Plain facts
| Fact | Hyro | Infermedica |
|---|---|---|
| Primary category | Patient Voice Agents | Clinical Decision Support |
| Founded | 2018 | Not recorded |
| Headquarters | New York, New York | Wrocław, Poland |
| Website | hyro.ai | infermedica.com |
Side by Side
Select any grade to read the note behind it.
Product updates
The latest logged changes from each vendor, newest first, each linked to its source.
Hyro
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Model / architecture
Hyro published a breakdown of the architecture behind its patient scheduling agent, disclosing that it orchestrates seven distinct smaller models rather than driving the workflow from one large language model.
Source -
EHR / interoperability
Hyro has launched a new integration with ServiceNow to deliver voice and digital self-service capabilities for health systems.
Source
Each vendor in one paragraph
Written to be quoted whole. Each paragraph opens the AI Health Index profile of the vendor: what the product is, who buys it and what it does.
Conversational AI agent platform for health systems and payers, covering the call center, website, text messaging and mobile apps. Agents handle appointment scheduling and management, provider and location search, prescription refill requests and status updates, frequently asked questions answered from sources the health system approves, MyChart password resets and IT help desk requests, handing complex calls to staff.
Source: AI Health Index, September 2026
Infermedica, based in Wrocław, Poland, builds clinical triage that takes a patient from an undifferentiated symptom to a recommended level of care. Its inference engine, which the company describes as probabilistic models built on modified Bayesian networks and machine learning methods, reasons over a physician curated Medical Knowledge Base of more than 1,800 symptoms, 900 conditions and 340 risk factors, choosing each next question from the answers so far and ending with the most probable causes and a five level care recommendation from self care to ambulance.
Source: AI Health Index, September 2026
Questions buyers ask
How do Hyro and Infermedica work with the EHR?
Hyro is listed on Epic's Showroom, where the listing describes appointment scheduling and management, prescription refills, MyChart password resets and provider and location searches, and the home page describes using Epic's APIs for patient record identification, scheduling management and prescription support: reading the record and writing to it.
The Triage module is listed in Epic's App Orchard to add symptom checking to MyChart, and the Intake module is integrated with ProAssist, with other record systems reached through the Infermedica API. Intake sends a structured pre-visit summary and a list of possible conditions to the physician, and Conversational Triage supports pre-fill from patient records and maps findings to ICD-10 and SNOMED. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 29, 2026. No vendor pays for placement.
How do Hyro and Infermedica handle patient data?
In Hyro's case, the privacy policy adds that anonymized or de-identified information may be used and shared without restriction, for example to improve the services, and that an internal retention policy prevents perpetual retention, with no periods given. By design the customer defines and restricts the knowledge sources an agent may use, and each foundation model step receives only the context it needs.
For Infermedica, the company states compliance with GDPR and HIPAA, encryption of patient interactions, configurable access controls and audit logs, and says the platform is designed to meet strict data residency requirements. What is retained from a symptom interview, and for how long, is not stated. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 29, 2026. No vendor pays for placement.
Which settings and specialties do Hyro and Infermedica cover?
With Hyro, coverage is organized by organization and channel rather than specialty: health systems, federally qualified health centers (sold on multilingual access), children's hospitals and payers (member and agent experience), across calls, websites, text and mobile apps, with an outbound line for ACA and Medicaid coverage renewal outreach.
In Infermedica's case, the company reports use in more than 30 countries and 26 languages and more than 27 million checkups. Validation covers part of that: vignette testing and deployment studies for Healthdirect Australia's nurse line and national digital front door, a Portuguese insurer's nurse line, a US medical group, Australian and Middle Eastern health plans, and one Turkish emergency department. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 29, 2026. No vendor pays for placement.
How much do Hyro and Infermedica leave to the clinician?
For Hyro, the responsible AI page says the design will 'eliminate' hallucinations and misleading responses by restricting data sources.
With Infermedica, the pre-triage voice agent gathers symptoms before a nurse picks up and sorts callers by clinical urgency, and its launch post says it can also guide a caller to self care, a live nurse or emergency care at any hour. From the AI Health Index, drawn from each vendor's own published materials and the regulatory record, verified September 29, 2026. No vendor pays for placement.
Related comparisons
Other published head to head assessments involving these vendors or their closest peers.
Both records were reviewed on this site in September 2026. Neither publishes a price. Both publish little about how their own AI is governed, and Infermedica's research page leaves out a study's higher undertriage.
Ask Infermedica for undertriage rates, and ask Hyro how a symptom question is handed off.